Current Bibliography

  1. Alvarado DM, Chen B, Iticovici M, Thaker AI, Dai N, VanDussen KL, Shaikh N, Lim CK, Guillemin GJ, Tarr PI, Ciorba MA. Epithelial Indoleamine 2,3-Dioxygenase 1 Modulates Aryl Hydrocarbon Receptor and Notch Signaling to Increase Differentiation of Secretory Cells and Alter Mucus-Associated Microbiota. Gastroenterology. 2019 Oct;157(4):1093-1108.e11doi: 10.1053/j.gastro.2019.07.013. Epub 2019 Jul 17. PubMed PMID: 31325428; PubMed Central PMCID: PMC6756966.
  2. Stenson WF, Makkar S, Riehl TE, Chen B, Yan Y, Ciorba MA, Alvarado DM. Hyaluronic acid binding to TLR4 promotes proliferation and blocks apoptosis in colon cancer. Mol Cancer Ther. 2019 Sep 4;doi: 10.1158/1535-7163.MCT-18-1225. [Epub ahead of print] PubMed PMID: 31484704; NIHMSID:NIHMS1539227.
  3. Kumar P, Kuhlmann FM, Chakraborty S, Bourgeois AL, Foulke-Abel J, Tumala B, Vickers TJ, Sack DA, DeNearing B, Harro CD, Wright WS, Gildersleeve JC, Ciorba MA, Santhanam S, Porter CK, Gutierrez RL, Prouty MG, Riddle MS, Polino A, Sheikh A, Donowitz M, Fleckenstein JM. Enterotoxigenic Escherichia coli-blood group A interactions intensify diarrheal severity. J Clin Invest. 2019 Jul 1;129(7):2980doi: 10.1172/JCI130874. Epub 2019 Jul 1. PubMed PMID: 31259744; PubMed Central PMCID: PMC6597215.
  4. Tsai R, Mintz A, Lin M, Mhlanga J, Chiplunker A, Salter A, Ciorba M, Deepak P, Fowler K. Magnetic resonance enterography features of small bowel Crohn’s disease activity: an inter-rater reliability study of small bowel active inflammation in clinical practice setting. Br J Radiol. 2019 Jul;92(1099):20180930doi: 10.1259/bjr.20180930. Epub 2019 May 29. PubMed PMID: 31141389; PubMed Central PMCID: PMC6636275.
  5. Rengarajan S, Vivio EE, Parkes M, Peterson DA, Roberson EDO, Newberry RD, Ciorba MA, Hsieh CS. Dynamic immunoglobulin responses to gut bacteria during inflammatory bowel disease. Gut Microbes. 2019 Jun 16;:1-16doi: 10.1080/19490976.2019.1626683. [Epub ahead of print] PubMed PMID: 31203722.
  6. Bishnupuri KS, Alvarado DM, Khouri AN, Shabsovich M, Chen B, Dieckgraefe BK, Ciorba MA. IDO1 and Kynurenine Pathway Metabolites Activate PI3K-Akt Signaling in the Neoplastic Colon Epithelium to Promote Cancer Cell Proliferation and Inhibit Apoptosis. Cancer Res. 2019 Mar 15;79(6):1138-1150doi: 10.1158/0008-5472.CAN-18-0668. Epub 2019 Jan 24. PubMed PMID: 30679179; PubMed Central PMCID: PMC6420842.
  7. McHenry S, Sharma Y, Tirath A, Tsai R, Mintz A, Fraum TJ, Salter A, Browning JD, Flores AG, Davidson NO, Fowler KJ, Ciorba MA, Deepak P. Crohn’s Disease Is Associated With an Increased Prevalence of Nonalcoholic Fatty Liver Disease: A Cross-Sectional Study Using Magnetic Resonance Proton Density Fat Fraction Mapping. Clin Gastroenterol Hepatol. 2019 Mar 12;doi: 10.1016/j.cgh.2019.02.045. [Epub ahead of print] PubMed PMID: 30876963.
  8. Li E, Zhang Y, Tian X, Wang X, Gathungu G, Wolber A, Shiekh SS, Sartor RB, Davidson NO, Ciorba MA, Zhu W, Nelson LM, Robertson CE, Frank DN. Influence of Crohn’s disease related polymorphisms in innate immune function on ileal microbiome. PLoS One. 2019;14(2):e0213108doi: 10.1371/journal.pone.0213108. eCollection 2019. PubMed PMID: 30818349; PubMed Central PMCID: PMC6395037.
  9. Gregory M, Weaver KN, Hoversten P, Hicks SB, Patel D, Ciorba MA, Gutierrez AM, Beniwal-Patel P, Palam S, Syal G, Herfarth HH, Christophi G, Raffals L, Barnes EL, Deepak P. Efficacy of Vedolizumab for Refractory Pouchitis of the Ileo-anal Pouch: Results From a Multicenter US Cohort. Inflamm Bowel Dis. 2019 Feb 27;doi: 10.1093/ibd/izz030. [Epub ahead of print] PubMed PMID: 30810748.
  10. Gregory MH, Ciorba MA, Deepak P, Christophi GP. Successful Treatment of Pyoderma Gangrenosum with Concomitant Tofacitinib and Infliximab. Inflamm Bowel Dis. 2019 Feb 8;doi: 10.1093/ibd/izz015. [Epub ahead of print] PubMed PMID: 30753456.
  11. Gregory MH, McKinnon A, Stwalley D, Hippensteel KJ, Loftus EV Jr, Ciorba MA, Olsen MA, Deepak P. Anti-Tumour Necrosis Factor Therapy for Inflammatory Bowel Diseases Do Not Impact Serious Infections after Arthroplasty. J Crohns Colitis. 2019 Feb 1;13(2):182-188doi: 10.1093/ecco-jcc/jjy148. PubMed PMID: 30256926; PubMed Central PMCID: PMC6548222.
  12. Ferreiro A, Dantas G, Ciorba MA. Insights into How Probiotics Colonize the Healthy Human Gut. Gastroenterology. 2019 Feb;156(3):820-822doi: 10.1053/j.gastro.2019.01.022. Epub 2019 Jan 16. PubMed PMID: 30659834.
  13. VanDussen KL, Stojmirović A, Li K, Liu TC, Kimes PK, Muegge BD, Simpson KF, Ciorba MA, Perrigoue JG, Friedman JR, Towne JE, Head RD, Stappenbeck TS. Abnormal Small Intestinal Epithelial Microvilli in Patients With Crohn’s Disease. Gastroenterology. 2018 Sep;155(3):815-828doi: 10.1053/j.gastro.2018.05.028. Epub 2018 May 18. PubMed PMID: 29782846; PubMed Central PMCID: PMC6378688.
  14. Kumar P, Kuhlmann FM, Chakraborty S, Bourgeois AL, Foulke-Abel J, Tumala B, Vickers TJ, Sack DA, DeNearing B, Harro CD, Wright WS, Gildersleeve JC, Ciorba MA, Santhanam S, Porter CK, Gutierrez RL, Prouty MG, Riddle MS, Polino A, Sheikh A, Donowitz M, Fleckenstein JM. Enterotoxigenic Escherichia coli-blood group A interactions intensify diarrheal severity. J Clin Invest. 2018 Aug 1;128(8):3298-3311doi: 10.1172/JCI97659. Epub 2018 Jun 25. PubMed PMID: 29771685; PubMed Central PMCID: PMC6063478.
  15. Riehl TE, Alvarado D, Ee X, Zuckerman A, Foster L, Kapoor V, Thotala D, Ciorba MA, Stenson WF. Lactobacillus rhamnosus GG protects the intestinal epithelium from radiation injury through release of lipoteichoic acid, macrophage activation and the migration of mesenchymal stem cells. Gut. 2018 Jun 22;doi: 10.1136/gutjnl-2018-316226. [Epub ahead of print] PubMed PMID: 29934438.
  16. Sofia MA, Ciorba MA, Meckel K, Lim CK, Guillemin GJ, Weber CR, Bissonnette M, Pekow JR. Tryptophan Metabolism through the Kynurenine Pathway is Associated with Endoscopic Inflammation in Ulcerative Colitis. Inflamm Bowel Dis. 2018 Jun 8;24(7):1471-1480doi: 10.1093/ibd/izy103. PubMed PMID: 29796641; PubMed Central PMCID: PMC6196764.
  17. Wardill HR, Van Sebille YZA, Ciorba MA, Bowen JM. Prophylactic probiotics for cancer therapy-induced diarrhoea: a meta-analysis. Curr Opin Support Palliat Care. 2018 Jun;12(2):187-197doi: 10.1097/SPC.0000000000000338. PubMed PMID: 29547491.
  18. Brown JW, Badahdah A, Iticovici M, Vickers TJ, Alvarado DM, Helmerhorst EJ, Oppenheim FG, Mills JC, Ciorba MA, Fleckenstein JM, Bullitt E. A Role for Salivary Peptides in the Innate Defense Against Enterotoxigenic Escherichia coli. J Infect Dis. 2018 Apr 11;217(9):1435-1441doi: 10.1093/infdis/jiy032. PubMed PMID: 29528423; PubMed Central PMCID: PMC5894089.
  19. Braga Neto MB, Gregory M, Ramos GP, Loftus EV Jr, Ciorba MA, Bruining DH, Bazerbachi F, Abu Dayyeh BK, Kushnir VM, Shah M, Collazo-Clavell ML, Raffals LE, Deepak P. De-novo Inflammatory Bowel Disease After Bariatric Surgery: A Large Case Series. J Crohns Colitis. 2018 Mar 28;12(4):452-457doi: 10.1093/ecco-jcc/jjx177. PubMed PMID: 29272375.
  20. Afzali A, Ciorba MA, Schwartz DA, Sharaf M, Fourment C, Ritter T, Wolf DC, Shafran I, Randall CW, Kane SV. Challenges in Using Real-world Clinical Practice Records for Validation of Clinical Trial Data in Inflammatory Bowel Disease: Lessons Learned. Inflamm Bowel Dis. 2017 Dec 19;24(1):2-4doi: 10.1093/ibd/izx015. PubMed PMID: 29272481.
  21. Park H, Chen B, Ciorba MA. Progress in PD-1-based Immunotherapy: New Mechanistic Insight May Provide Expanded Hope for Application to Colon and Gastrointestinal Cancers. Gastroenterology. 2017 Oct;153(4):1162-1163doi: 10.1053/j.gastro.2017.08.050. Epub 2017 Sep 1. PubMed PMID: 28867277.
  22. Walker T, Ciorba M, Dubberke ER. Reducing Fluoroquinolone Use Is a Key Step in Controlling the Burden of Clostridium difficile Infection. Gastroenterology. 2017 Aug;153(2):606-607doi: 10.1053/j.gastro.2017.06.048. Epub 2017 Jun 28. PubMed PMID: 28668696.
  23. Sheikh A, Rashu R, Begum YA, Kuhlman FM, Ciorba MA, Hultgren SJ, Qadri F, Fleckenstein JM. Highly conserved type 1 pili promote enterotoxigenic E. coli pathogen-host interactions. PLoS Negl Trop Dis. 2017 May;11(5):e0005586doi: 10.1371/journal.pntd.0005586. eCollection 2017 May. PubMed PMID: 28531220; PubMed Central PMCID: PMC5456409.
  24. Ciorba M. Chapter 41 – The Prevention and Treatment of Radiation and Chemotherapy-Induced Intestinal Mucositis A2 – Floch, Martin H. Ringel Y, Walker W, editors. Boston: Academic Press; 2017///. 383-387p.
  25. Kuhlmann FM, Santhanam S, Kumar P, Luo Q, Ciorba MA, Fleckenstein JM. Blood Group O-Dependent Cellular Responses to Cholera Toxin: Parallel Clinical and Epidemiological Links to Severe Cholera. Am J Trop Med Hyg. 2016 Aug 3;95(2):440-3doi: 10.4269/ajtmh.16-0161. Epub 2016 May 9. PubMed PMID: 27162272; PubMed Central PMCID: PMC4973196.
  26. Cushing KC, Kanuri N, Ciorba MA. Pneumococcal Disease in Inflammatory Bowel Disease: Justification to Vaccinate at Diagnosis. Gastroenterology. 2016 Aug;151(2):365-6doi: 10.1053/j.gastro.2016.06.027. Epub 2016 Jun 30. PubMed PMID: 27375193; PubMed Central PMCID: PMC5438198.
  27. Patel A, Hasak S, Cassell B, Ciorba MA, Vivio EE, Kumar M, Gyawali CP, Sayuk GS. Effects of disturbed sleep on gastrointestinal and somatic pain symptoms in irritable bowel syndrome. Aliment Pharmacol Ther. 2016 Aug;44(3):246-58doi: 10.1111/apt.13677. Epub 2016 May 30. PubMed PMID: 27240555; PubMed Central PMCID: PMC5020700.
  28. Dey N, Ciorba MA. Probiotic Gut Bacteria Enhance Cancer Immunotherapy in a Mouse Model of Melanoma. Gastroenterology. 2016 Jul;151(1):206-7doi: 10.1053/j.gastro.2016.05.015. Epub 2016 May 26. PubMed PMID: 27238844.
  29. Ciorba MA. Advances in understanding and improving gastrointestinal symptoms during supportive and palliative care: a decade of progress. Curr Opin Support Palliat Care. 2016 Jun;10(2):149-51doi: 10.1097/SPC.0000000000000215. PubMed PMID: 27054289; PubMed Central PMCID: PMC5359016.
  30. Christophi GP, Rengarajan A, Ciorba MA. Rectal budesonide and mesalamine formulations in active ulcerative proctosigmoiditis: efficacy, tolerance, and treatment approach. Clin Exp Gastroenterol. 2016;9:125-30doi: 10.2147/CEG.S80237. eCollection 2016. Review. PubMed PMID: 27274301; PubMed Central PMCID: PMC4876845.
  31. Vivio EE, Kanuri N, Gilbertsen JJ, Monroe K, Dey N, Chen CH, Gutierrez AM, Ciorba MA. Vedolizumab Effectiveness and Safety Over the First Year of Use in an IBD Clinical Practice. J Crohns Colitis. 2016 Apr;10(4):402-9doi: 10.1093/ecco-jcc/jjv226. Epub 2015 Dec 17. PubMed PMID: 26681763; PubMed Central PMCID: PMC4946762.
  32. Santhanam S, Alvarado DM, Ciorba MA. Therapeutic targeting of inflammation and tryptophan metabolism in colon and gastrointestinal cancer. Transl Res. 2016 Jan;167(1):67-79doi: 10.1016/j.trsl.2015.07.003. Epub 2015 Aug 3. Review. PubMed PMID: 26297050; PubMed Central PMCID: PMC4684437.
  33. Riehl TE, Santhanam S, Foster L, Ciorba M, Stenson WF. CD44 and TLR4 mediate hyaluronic acid regulation of Lgr5+ stem cell proliferation, crypt fission, and intestinal growth in postnatal and adult mice. Am J Physiol Gastrointest Liver Physiol. 2015 Dec 1;309(11):G874-87doi: 10.1152/ajpgi.00123.2015. Epub 2015 Oct 1. PubMed PMID: 26505972; PubMed Central PMCID: PMC4669354.
  34. Cushing K, Alvarado DM, Ciorba MA. Butyrate and Mucosal Inflammation: New Scientific Evidence Supports Clinical Observation. Clin Transl Gastroenterol. 2015 Aug 27;6:e108doi: 10.1038/ctg.2015.34. PubMed PMID: 26312412; PubMed Central PMCID: PMC4816278.
  35. Ciorba MA. Scap and the intestinal epithelial stem cell niche: new insights from lipid biology. J Lipid Res. 2015 Aug;56(8):1381-2doi: 10.1194/jlr.C061309. Epub 2015 Jun 10. PubMed PMID: 26063459; PubMed Central PMCID: PMC4513980.
  36. Christophi GP, Ciorba MA. Lower Dose Infliximab for Ulcerative Colitis: How Low Can We Go and How Much Can be Saved?. J Clin Gastroenterol. 2015 Aug;49(7):539-40doi: 10.1097/MCG.0000000000000352. PubMed PMID: 26057322; PubMed Central PMCID: PMC4741379.
  37. Lee A, Kanuri N, Zhang Y, Sayuk GS, Li E, Ciorba MA. Correction: IDO1 and IDO2 Non-Synonymous Gene Variants: Correlation with Crohn’s Disease Risk and Clinical Phenotype. PLoS One. 2015;10(7):e0133098doi: 10.1371/journal.pone.0133098. eCollection 2015. PubMed PMID: 26173109; PubMed Central PMCID: PMC4501741.
  38. VanDussen KL, Marinshaw JM, Shaikh N, Miyoshi H, Moon C, Tarr PI, Ciorba MA, Stappenbeck TS. Development of an enhanced human gastrointestinal epithelial culture system to facilitate patient-based assays. Gut. 2015 Jun;64(6):911-20doi: 10.1136/gutjnl-2013-306651. Epub 2014 Jul 9. PubMed PMID: 25007816; PubMed Central PMCID: PMC4305344.
  39. Ciorba MA, Hallemeier CL, Stenson WF, Parikh PJ. Probiotics to prevent gastrointestinal toxicity from cancer therapy: an interpretive review and call to action. Curr Opin Support Palliat Care. 2015 Jun;9(2):157-62doi: 10.1097/SPC.0000000000000134. Review. PubMed PMID: 25872116; PubMed Central PMCID: PMC4852157.
  40. Lee A, Kanuri N, Zhang Y, Sayuk GS, Li E, Ciorba MA. IDO1 and IDO2 non-synonymous gene variants: correlation with crohn’s disease risk and clinical phenotype. PLoS One. 2014;9(12):e115848doi: 10.1371/journal.pone.0115848. eCollection 2014. PubMed PMID: 25541686; PubMed Central PMCID: PMC4277413.
  41. Iskandar HN, Cassell B, Kanuri N, Gyawali CP, Gutierrez A, Dassopoulos T, Ciorba MA, Sayuk GS. Tricyclic antidepressants for management of residual symptoms in inflammatory bowel disease. J Clin Gastroenterol. 2014 May-Jun;48(5):423-9doi: 10.1097/MCG.0000000000000049. PubMed PMID: 24406434; PubMed Central PMCID: PMC4111227.
  42. Ciorba MA. Kynurenine pathway metabolites: relevant to vitamin B-6 deficiency and beyond. Am J Clin Nutr. 2013 Oct;98(4):863-4doi: 10.3945/ajcn.113.072025. Epub 2013 Aug 28. PubMed PMID: 23985806; PubMed Central PMCID: PMC4498264.
  43. Thaker AI, Rao MS, Bishnupuri KS, Kerr TA, Foster L, Marinshaw JM, Newberry RD, Stenson WF, Ciorba MA. IDO1 metabolites activate β-catenin signaling to promote cancer cell proliferation and colon tumorigenesis in mice. Gastroenterology. 2013 Aug;145(2):416-25.e1-4doi: 10.1053/j.gastro.2013.05.002. Epub 2013 May 10. PubMed PMID: 23669411; PubMed Central PMCID: PMC3722304.
  44. Ciorba MA. Indoleamine 2,3 dioxygenase in intestinal disease. Curr Opin Gastroenterol. 2013 Mar;29(2):146-52doi: 10.1097/MOG.0b013e32835c9cb3. Review. PubMed PMID: 23283180; PubMed Central PMCID: PMC3686557.
  45. Thaker AI, Shaker A, Rao MS, Ciorba MA. Modeling colitis-associated cancer with azoxymethane (AOM) and dextran sulfate sodium (DSS). J Vis Exp. 2012 Sep 11;(67)doi: 10.3791/4100. PubMed PMID: 22990604; PubMed Central PMCID: PMC3490277.
  46. Ciorba MA. A gastroenterologist’s guide to probiotics. Clin Gastroenterol Hepatol. 2012 Sep;10(9):960-8doi: 10.1016/j.cgh.2012.03.024. Epub 2012 Apr 10. Review. PubMed PMID: 22504002; PubMed Central PMCID: PMC3424311.
  47. Gupta NK, Thaker AI, Kanuri N, Riehl TE, Rowley CW, Stenson WF, Ciorba MA. Serum analysis of tryptophan catabolism pathway: correlation with Crohn’s disease activity. Inflamm Bowel Dis. 2012 Jul;18(7):1214-20doi: 10.1002/ibd.21849. Epub 2011 Aug 5. PubMed PMID: 21823214; PubMed Central PMCID: PMC3235239.
  48. Ciorba MA, Riehl TE, Rao MS, Moon C, Ee X, Nava GM, Walker MR, Marinshaw JM, Stappenbeck TS, Stenson WF. Lactobacillus probiotic protects intestinal epithelium from radiation injury in a TLR-2/cyclo-oxygenase-2-dependent manner. Gut. 2012 Jun;61(6):829-38doi: 10.1136/gutjnl-2011-300367. Epub 2011 Oct 24. PubMed PMID: 22027478; PubMed Central PMCID: PMC3345937.
  49. Iskandar HN, Ciorba MA. Biomarkers in inflammatory bowel disease: current practices and recent advances. Transl Res. 2012 Apr;159(4):313-25doi: 10.1016/j.trsl.2012.01.001. Epub 2012 Feb 1. Review. PubMed PMID: 22424434; PubMed Central PMCID: PMC3308116.
  50. Kerr TA, Ciorba MA, Matsumoto H, Davis VR, Luo J, Kennedy S, Xie Y, Shaker A, Dieckgraefe BK, Davidson NO. Dextran sodium sulfate inhibition of real-time polymerase chain reaction amplification: a poly-A purification solution. Inflamm Bowel Dis. 2012 Feb;18(2):344-8doi: 10.1002/ibd.21763. Epub 2011 May 25. PubMed PMID: 21618356; PubMed Central PMCID: PMC3600644.